The Alpha Series combines the abilities of both Rosie and Bouncer, as it can use all of the Big Daddy's weapons (a.k.a. the drill and rivet gun). It even has an upraded rivet gun known as the Magnum Rivet. Unfortunately, the Magnum Rivet has less ammo and is less accurate than the original, but it is far stronger, as it can kill most splicers in a single it.
Trivia: the BioShock 2 "Hunting the Big Sister" trailer uses a Rosie skin for Subject Delta.