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In BioShock 2, if you don't pick up any free Plasmids or Gene Tonics it costs 6090 ADAM to buy everything. If you pick up all the free items, then it costs 4905 ADAM.

The total cost in BioShock is more complicated because each item may cost more or less in different levels. Check out the price tables on the BioShock Wiki for more information:

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